HC Wainwright & Co. Upholds Buy Rating for Immunic (IMUX)
Analyst Recommendation: HC Wainwright & Co. has maintained a Buy recommendation for Immunic (NasdaqGS:IMUX), with a projected one-year price target of $6.41/share, indicating a potential upside of 718.72% from its current price of $0.78/share.
Fund Sentiment: There has been a 15.79% increase in the number of funds reporting positions in Immunic, with total shares owned by institutions rising by 7.50% to 52,173K shares.
Shareholder Activity: Notable shareholders include Standard Life Aberdeen and Bvf, with no changes in their holdings, while Tekla Life Sciences Investors significantly increased their stake by 76.60%.
Market Outlook: The put/call ratio for IMUX is 0.03, suggesting a bullish sentiment among investors regarding the stock's future performance.
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Immunic Completes Enrollment for Phase 3 Trials of Vidofludimus Calcium in MS, Top-Line Data Expected by End of 2026
- Trial Enrollment Completion: Immunic has completed enrollment of 2,221 patients across over 100 sites in 15 countries for its Phase 3 ENSURE-1 and ENSURE-2 trials, with top-line data expected by the end of 2026, which will provide critical clinical evidence for multiple sclerosis treatment.
- Positive Clinical Data: The Phase 2 CALLIPER trial demonstrated that Vidofludimus Calcium significantly reduced the 24-week confirmed disability worsening rate in progressive multiple sclerosis patients, achieving positive effects even in those without baseline inflammatory markers, reinforcing its neuroprotective mechanism potential.
- Long-Term Safety Data: In the Phase 2 EMPhASIS trial, 92.3% of patients remained free of confirmed disability worsening events at week 144, indicating good long-term safety and tolerability of Vidofludimus Calcium, potentially offering patients greater independence.
- Intellectual Property Protection: Immunic received a Notice of Allowance from the USPTO for dose strengths of Vidofludimus Calcium in progressive multiple sclerosis, with intellectual property protection extending to 2041, enhancing the company's competitive position in the market.

Immunic Completes Enrollment for Phase 3 Trials of Vidofludimus Calcium, Top-Line Data Expected by End of 2026
- Trial Enrollment Completed: Immunic has completed enrollment for its twin Phase 3 ENSURE trials of Vidofludimus Calcium in relapsing multiple sclerosis, with top-line data expected by the end of 2026, which will significantly bolster the company's leadership position in the neurology sector.
- Efficacy Data Significant: Phase 2 CALLIPER trial results demonstrated that Vidofludimus Calcium significantly reduced confirmed disability worsening events over 24 weeks and increased disability improvement rates, indicating the drug's potential to reshape treatment paradigms in multiple sclerosis.
- Long-Term Safety Profile: Long-term open-label data from the Phase 2 EMPhASIS trial showed that a substantial majority of patients remained free from confirmed disability worsening events during follow-up, highlighting Vidofludimus Calcium's safety and tolerability in long-term management, thereby enhancing patient quality of life.
- Strengthened Intellectual Property: The U.S. has granted a patent for dose strengths of Vidofludimus Calcium in progressive multiple sclerosis, extending intellectual property protection until 2041, which will provide Immunic with a stronger competitive edge and commercialization potential.






