CSPC Pharma Collaborates with AstraZeneca on Long-Acting Peptide Medicines, Securing Over $9.3B Upfront Payment, Despite 10% Drop in Share Price
CSPC Pharma Collaboration: CSPC Pharma has entered a strategic collaboration with AstraZeneca for developing long-acting peptide medicines, leveraging its proprietary technology and AI-driven drug discovery platform.
Financial Terms: The agreement includes an upfront payment of $1.2 billion, with potential additional payments of up to $3.5 billion for R&D milestones and $13.8 billion for sales milestones, plus royalties on net sales.
Stock Performance: Following the announcement, CSPC Pharma's stock opened 2.34% higher but later fell by 10.1%, closing at $9.61 with significant trading volume.
Short Selling Activity: CSPC Pharma has reported short selling of $160.35 million, with a short selling ratio of 14.568%.
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Short Selling Activity Reaches $24.7B, Representing 17.3% of Eligible Securities Turnover by Midday
Short Selling Turnover: The short selling turnover in the Hong Kong market reached $24.7 billion at midday, accounting for 17.3% of the eligible securities turnover, an increase from 16.4% on the previous trading day.
Top Short Selling Shares: The top five shares with the highest short selling amounts include TRACKER FUND (02800.HK) with $5.12 billion, HSCEI ETF (02828.HK) with $2.60 billion, CSPC PHARMA (01093.HK) with $888.54 million, CSOP HS TECH (03033.HK) with $733.09 million, and ZIJIN MINING (02899.HK) with $680.34 million.
Short Selling Ratios: TRACKER FUND has the highest short selling ratio at 55.7%, followed by HSCEI ETF at 43.4%, CSPC PHARMA at 23.1%, CSOP HS TECH at 15.6%, and ZIJIN MINING at 13.7%.
Market Data Note: The stock quotes for Hong Kong stocks are delayed by at least 15 minutes, and the short selling data is as of January 30, 2026, at 12:25 PM.

HSI Drops 498 Points at Noon; Commodity Shares Tumble; CSPC Pharma Falls Over 12%
Market Reaction to Fed Chair Nominee: The DXY rose following President Trump's announcement of the Fed Chair nominee, while the Hong Kong stock market experienced significant declines, with the HSI dropping 498 points or 1.8% by the morning session's close.
Gold and Mining Stocks Performance: Gold prices fell over 3%, leading to substantial losses in mining stocks such as SD GOLD and ZIJIN GOLD, which plunged 12.9% and 10% respectively, alongside other mining companies experiencing similar declines.
Pharmaceutical Sector Developments: CSPC PHARMA's stock plummeted 12.5% despite a partnership with AstraZeneca for drug development, which included an upfront payment exceeding HKD9.3 billion.
Corporate News and Market Rumors: The Panama Supreme Court ruled contracts for two local ports unconstitutional, negatively impacting CKH HOLDINGS, while rumors of a potential ownership change at NEW WORLD DEV led to a 3.7% increase in its stock price.









