Compugen Reports Third Quarter 2025 Results
Clinical Trials Update: Compugen presented Phase 1 data for COM701 at ESMO 2025, showing promising results in platinum-resistant ovarian cancer, and is currently enrolling patients in the MAIA-ovarian platform trial with interim analysis expected in Q1 2027.
Partnership Developments: AstraZeneca shared positive results for rilvegostomig in NSCLC and bladder cancer at ESMO 2025, highlighting the potential of their Fc-reduced anti-TIGIT antibody format, which may improve efficacy and safety.
Financial Position: Compugen reported a cash position of approximately $86.1 million as of September 30, 2025, with expectations to fund operations into Q3 2027, despite a net loss of about $6.98 million for the third quarter.
Pipeline and Future Prospects: The company is advancing its immuno-oncology pipeline, including GS-0321, an anti-IL-18 binding protein antibody licensed to Gilead, and aims to leverage its AI/ML platform for novel cancer therapies.
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HC Wainwright Initiates Buy on Jade Biosciences with $25 Price Target
- Rating Initiation: HC Wainwright & Co. analyst Arthur He initiated coverage on Jade Biosciences Inc (NASDAQ:JBIO) with a Buy rating and a price target of $25, reflecting confidence in the company's future growth potential.
- Market Performance: Jade Biosciences shares closed at $13.17 on Tuesday, and the analyst's target price implies an upside of over 89%, which could attract more investor interest in the stock.
- Industry Outlook: With the ongoing development in the biotech sector, Jade Biosciences' new products and technologies are expected to drive market share growth, and the positive rating may further enhance market confidence in the company.
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Compugen Agrees with AstraZeneca to Monetize Future Royalties of Rilvegostomig
- Financial Strengthening: Compugen's agreement with AstraZeneca to monetize future royalties from rilvegostomig is expected to enhance its financial position, extending its cash runway into 2029 and providing ongoing support for its innovative immuno-oncology pipeline.
- Strategic Collaboration: The amended exclusive license agreement aims to bolster Compugen's capabilities in immuno-oncology, reflecting the significant potential value of rilvegostomig and further solidifying the company's market position in cancer treatment.
- Pipeline Expansion: Rilvegostomig, a PD-1/TIGIT bispecific antibody developed in collaboration with AstraZeneca, is currently in Phase 3 development, highlighting its importance in clinical trials and potential as a key future product.
- Innovative Platform Utilization: Compugen leverages its AI/ML-powered computational discovery platform (Unigen™) to identify novel drug targets, advancing the development of immunotherapies and showcasing the company's technological advantages and market potential in cancer treatment.









