Cocrystal Pharma Reports First Quarter 2025 Financial Results and Provides Updates on its Antiviral Drug-Development Programs
Cocrystal Pharma's Antiviral Developments: Cocrystal Pharma is advancing its antiviral product pipeline, particularly the oral pan-viral protease inhibitor CDI-988, which has shown broad-spectrum activity against norovirus and coronaviruses. The company plans to initiate a human challenge study for CDI-988 soon, aiming to provide effective treatment options for these viral infections.
Financial Performance Overview: In the first quarter of 2025, Cocrystal reported a net loss of $2.3 million, a decrease from $4.0 million in the same period of 2024, alongside reduced research and development expenses. The company's cash reserves were noted at $6.9 million as of March 31, 2025, reflecting ongoing efforts to maintain a capital-efficient business model.
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Cocrystal Receives IRB Approval to Initiate CDI-988 Clinical Trial, Enrollment Expected Q1 2026
- Clinical Trial Approval: Cocrystal Pharma has received approval from the Emory University Institutional Review Board to initiate a Phase 1b human challenge study for CDI-988, with enrollment expected to begin in Q1 2026, aiming to evaluate its efficacy in preventing and treating norovirus infections.
- Innovative Drug Development: CDI-988 is the first oral broad-spectrum antiviral drug specifically designed to inhibit the 3CL protease of all noroviruses, potentially revolutionizing management in high-risk environments such as hospitals and nursing homes.
- Global Health Impact: With norovirus causing approximately 700 million infections annually, Cocrystal's research addresses this significant global health challenge, which could substantially reduce cases of acute gastroenteritis and associated societal costs.
- Technological Platform Advantage: Leveraging its proprietary structure-based drug discovery platform, Cocrystal aims to rapidly develop novel antiviral agents, and the success of CDI-988 will further solidify its leadership position in the antiviral space, driving future growth for the company.

Cocrystal Pharma to Present Clinical Progress at NobleCon 21
- Conference Presentation: Cocrystal Pharma's CFO and co-CEO James Martin will present a company overview and clinical progress update at NobleCon 21 on December 3, 2025, showcasing the latest advancements in antiviral treatments.
- Investor Participation: The conference invites interested investors and guests to attend at a discounted rate, aiming to increase visibility and engagement within the small and micro-cap market.
- Webcast Availability: A video of Cocrystal's presentation will be available on December 4 and archived for 90 days on the company's website, ensuring that investors unable to attend live can access critical information.
- Company Background: Cocrystal Pharma is a clinical-stage biotechnology firm focused on developing innovative antiviral treatments for diseases such as influenza, viral gastroenteritis, COVID, and hepatitis, leveraging unique structure-based technologies and Nobel Prize-winning expertise to create first-in-class antiviral drugs.






