Clearmind Completes Patient Enrollment for Second Cohort of CMND-100 Trial
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 16 2025
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Source: Newsfilter
- Successful Patient Enrollment: Clearmind Medicine has successfully enrolled six patients for the second cohort in its FDA-approved Phase I/IIa trial of CMND-100, reflecting strong interest from clinical centers and potentially accelerating innovative treatment for AUD.
- Rapid Progress: The swift recruitment of the second cohort highlights the operational efficiency of collaborating with premier clinical sites like Johns Hopkins University, which may lead to faster clinical data generation and market opportunities for the company.
- Safety and Efficacy: The first cohort's trial results demonstrated a favorable safety profile and preliminary efficacy signals, indicating that CMND-100 could provide new solutions for treating AUD, addressing the needs of millions of patients worldwide.
- Future Outlook: With dosing for the second cohort expected to commence shortly, Clearmind anticipates topline results in the coming months, which will lay the groundwork for further development in the psychedelic pharmaceutical space.
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Analyst Views on CMND
About CMND
Clearmind Medicine Inc. is a psychedelic pharmaceutical biotech company. The Company is focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorders. The Company researches and develops psychedelic-based compounds and attempts to commercialize them as regulated medicines, foods, or supplements. The Company’s intellectual portfolio consists of 19 patent families including 31 granted patents.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Clearmind Regains Nasdaq Compliance with Share Price Above $1
- Compliance Restoration: Clearmind Medicine confirmed on December 30, 2025, that its common shares have maintained a closing price above $1 for the last 10 consecutive trading days, successfully regaining compliance with Nasdaq Listing Rule 5550(a)(2), indicating positive progress in stock price stability.
- Price Volatility Context: Previously, Clearmind was notified on December 4, 2025, of non-compliance due to its share price being below $1 for over 30 consecutive trading days, and this compliance restoration is expected to enhance investor confidence and attract more capital inflow.
- Market Reaction Expectations: With the restoration of compliance, Clearmind is likely to improve its market image and bolster investor confidence in its future growth potential, particularly in light of its commitment to developing novel psychedelic treatment solutions.
- Strategic Development Focus: Clearmind is currently focused on developing neuroplastic drugs targeting under-treated health issues and will continue to seek patent protection to enhance its intellectual property portfolio, further strengthening its competitiveness in the biotech sector.
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Clearmind Regains Nasdaq Compliance with Share Price Above $1
- Compliance Regained: Clearmind Medicine received confirmation from Nasdaq on December 30, 2025, that its share price exceeded $1 for the last 10 consecutive trading days, thereby regaining compliance with Nasdaq Listing Rule 5550(a)(2) and resolving previous compliance issues.
- Price Fluctuation Context: The company was notified on December 4, 2025, of non-compliance due to its common shares closing below $1 for over 30 consecutive trading days, highlighting market concerns regarding its stock price volatility.
- Future Growth Potential: Clearmind focuses on developing novel neuroplastogen-derived therapeutics, particularly for alcohol use disorder, which is expected to attract more investor interest in its innovative treatment solutions, further stabilizing and potentially increasing the company's stock price.
- Intellectual Property Strategy: The company currently holds 19 patent families and 31 granted patents, with plans to seek additional patents to enhance its market competitiveness, demonstrating a long-term strategic vision in the biotechnology sector.
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