Cabaletta Bio's Resecabtagene Autoleucel Granted FDA Orphan Designation
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 10 2025
0mins
Cabaletta Bio's treatment of myasthenia gravis, resecabtagene autoleucel, was granted FDA orphan designation, according to a post to the agency's website.
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Analyst Views on CABA
Wall Street analysts forecast CABA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CABA is 15.86 USD with a low forecast of 4.00 USD and a high forecast of 30.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
9 Analyst Rating
8 Buy
1 Hold
0 Sell
Strong Buy
Current: 2.850
Low
4.00
Averages
15.86
High
30.00
Current: 2.850
Low
4.00
Averages
15.86
High
30.00
About CABA
Cabaletta Bio, Inc. is a clinical-stage biotechnology company focused on the discovery and development of engineered T cell therapies that have the potential to provide deep and durable, perhaps curative, responses with one-time administration for patients with autoimmune diseases. Its Cabaletta Approach to B cell Ablation (CABA) platform encompasses two strategies: Chimeric Antigen Receptor T cells for Autoimmunity (CARTA) and Chimeric AutoAntibody Receptor T cells (CAART). Resecabtagene autoleucel, its lead product candidate from its CARTA platform, is a 4-1BB co-stimulatory domain-containing fully human CD19-CAR T construct designed to treat patients with a range of autoimmune diseases. Its DSG3-CAART product candidate is being evaluated for the treatment of mPV, a subtype of PV that affects the epithelium of the mucous membranes, in the Phase 1 DesCAARTes TM trial. Its MuSK-CAART product candidate is designed to treat a subset of patients with MG, targeting autoreactive B cells.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Cabaletta Bio (CABA) Shares Surge 11% Following Insider Purchases
- Insider Purchases: Cabaletta Bio's General Counsel, Michael Gerard, purchased 6,600 shares on January 21, 2026, totaling $14,979, indicating strong confidence in the company's future prospects.
- CMO Acquisition: Chief Medical Officer Chang David J. acquired 8,800 shares at an average price of $2.26 per share, reflecting executive recognition of the company's value and optimism about future performance.
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- Market Reaction: Following the insider purchases, Cabaletta Bio's shares surged 11% on Thursday, reflecting investor optimism regarding the company's future developments.
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