Aspire Biopharma Files Provisional Patent for Sublingual Clopidogrel Powder
Aspire Biopharma announced the filing of a new provisional patent application with the United States Patent and Trademark Office. The application, titled "A Sublingual Powder Formulation of Clopidogrel and Methods of Use Thereof," covers the first-ever sublingual formulation of clopidogrel, the active pharmaceutical ingredient in the widely prescribed blood thinner Plavix. This development represents a series of sublingual-based therapeutic alternatives the Company intends to commercialize via the FDA's 505(b)(2) regulatory pathway. Aspire's strategic pipeline focuses on reformulating approved generic therapeutics to address unmet needs where no sublingual alternatives currently exist, thus bringing the benefits of reducing or eliminating gastric irritation to products with these known side effects.
Get Free Real-Time Notifications for Any Stock
Analyst Views on ASBP
About ASBP
About the author
Aspire Biopharma Submits Pre-IND Request to FDA for Fast-Acting Sublingual Aspirin with Significant Clinical Benefits
- FDA Submission Progress: Aspire submitted its Pre-IND meeting request to the FDA on November 3, 2025, for its fast-acting sublingual aspirin, marking a significant milestone that is expected to accelerate the clinical development process toward potential FDA approval.
- Breakthrough Clinical Data: Clinical trials demonstrated that Aspire's sublingual aspirin inhibits platelet aggregation in under two minutes, acting approximately four to five times faster than chewed aspirin, which holds significant clinical implications for improving treatment outcomes in heart attack patients.
- Substantial Market Potential: With over 800,000 people in the U.S. experiencing heart attacks annually, Aspire's product could provide a faster and more reliable treatment option, addressing the urgent market demand for effective medical solutions.
- Optimized Regulatory Pathway: Aspire plans to pursue a 505(b)(2) regulatory pathway, which allows the FDA to consider data from previously approved drugs, potentially reducing development time and costs, thereby enhancing its competitive position in the market.
Gorilla Technology Shares Rise Approximately 14%; Check Out 20 Stocks Making Moves in Premarket Trading
Gorilla Technology Group Performance: Gorilla Technology Group Inc. reported a 32% year-over-year revenue increase to $26.5 million for Q3, leading to a 13.7% rise in its share price during pre-market trading.
Other Gainers in Pre-Market Trading: Notable stocks that surged include Olema Pharmaceuticals (up 53%), Lobo Technologies (up 40.3%), and Aspire Biopharma (up 30.7%), among others.
Losers in Pre-Market Trading: LifeMD Inc. saw a significant drop of 26.2% after disappointing financial results, while Alpha Technology Group and NextPlat Corp also experienced notable declines.
Market Overview: The pre-market trading session showed a mix of gains and losses across various stocks, with some companies reporting strong earnings while others faced setbacks.
