Invivyd Sets Price for $125 Million Public Offering of Common Stock and Pre-Funded Warrants
Public Offering Announcement: Invivyd, Inc. has priced an underwritten public offering of 44 million shares of common stock at $2.50 per share, along with pre-funded warrants for 6 million shares at $2.4999 each, aiming to raise approximately $125 million before expenses.
Use of Proceeds: The company plans to utilize the net proceeds for commercial preparedness for the potential launch of VYD2311, ongoing research and development for its pipeline programs, and general corporate purposes.
Underwriters and Closing Details: Cantor is the sole book-running manager for the offering, with an option for underwriters to purchase an additional 7.5 million shares. The offering is expected to close around November 19, 2025, pending customary closing conditions.
Company Background: Invivyd is a biopharmaceutical company focused on developing antibodies for serious viral infectious diseases, having received emergency use authorization for a monoclonal antibody in March 2024.
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Invivyd Initiates Phase 2 Trial for VYD2311 Targeting Long COVID Patients
- Trial Launch: Invivyd announced plans to initiate a Phase 2 clinical trial for VYD2311 targeting individuals with Long COVID and vaccine injury by mid-2026, addressing the urgent need for effective treatment options for millions suffering from persistent symptoms.
- Antibody Dose Design: The trial will utilize multiple high doses of monoclonal antibody VYD2311, which has demonstrated in vitro antiviral activity against all clinically recorded variants of SARS-CoV-2, potentially offering long-term therapeutic benefits for patients.
- Collaborative Research Group: Invivyd is partnering with the SPEAR Study Group to deepen the understanding of Long COVID biology and potential relief strategies, highlighting the focus on chronic infection and antigen persistence, which may open new avenues for treatment.
- Patient Recruitment Criteria: The trial will enroll patients with evidence of persistent infection or antigenemia, employing a double-blind placebo-controlled design to assess clinical efficacy and Patient-Reported Outcomes, ensuring scientific rigor and effectiveness of the study.

Invivyd Reports Q4 2025 Revenue of $17.2M, Up 25% Year-over-Year
- Revenue Growth: Invivyd reported preliminary Q4 2025 net product revenue of $17.2 million for PEMGARDA® (pemivibart), reflecting a 25% year-over-year increase and a 31% quarter-over-quarter rise, indicating strong market demand for monoclonal antibody prophylaxis.
- Strong Financial Position: After raising over $200 million in the second half of 2025, Invivyd anticipates ending 2025 with cash and cash equivalents of $226.7 million, providing ample funding for upcoming clinical trials and potential product launches.
- Clinical Trial Initiation: The company initiated the DECLARATION Phase 3 clinical trial in December 2025 to evaluate the safety and efficacy of VYD2311 in preventing COVID, with top-line data expected in mid-2026, which could significantly enhance the company's market position in COVID prevention.
- Pipeline Expansion: Invivyd nominated the potential best-in-class RSV antibody candidate VBY329 for preclinical development, aiming for IND readiness in 2H 2026, targeting a blockbuster market projected to reach $3-4 billion in annual revenues globally by 2030.









