Anebulo Pharmaceuticals Begins Dosing First Patients in Phase 1 Study of Intravenous Selonabant for Acute Cannabis-Induced Toxicity
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Sep 25 2025
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Source: Newsfilter
Phase 1 Study Announcement: Anebulo Pharmaceuticals has initiated a Phase 1 single ascending dose study of intravenous selonabant in healthy young adults, supported by a $994,300 grant from the National Institute on Drug Abuse (NIDA).
Focus on Pediatric Treatment: The company is prioritizing the development of an intravenous formulation of selonabant as a potential emergency antidote for acute cannabis-induced toxicity in children, who are more vulnerable to severe effects from cannabis exposure.
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About ANEB
Anebulo Pharmaceuticals, Inc. is a clinical-stage biotechnology company. It is engaged in developing treatments for cannabis toxicity, such as unintentional cannabis poisoning, acute cannabinoid intoxication (ACI) and the landscape of acute cannabis-induced conditions. Its lead product candidate is selonabant, a potent, small molecule antagonist of cannabinoid binding receptor type-1 (CB1), the primary receptor involved in the psychotropic effects of cannabinoids, with the potential to address the unmet medical need for a therapy to treat cannabis toxicity. Selonabant is orally bioavailable, rapidly absorbed, and has also been formulated for intravenous administration. Selonabant is intended to rapidly reverse the negative effects of cannabis-induced toxicity and reduce time to recovery. It is also prioritizing the advancement of a selonabant intravenous (IV) formulation as a potential treatment for pediatric patients with cannabis-induced CNS depression.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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