Adlai Nortye Secures RMB 1.6 Billion Exclusive Licensing Deal with ASK Pharm
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 29 2025
0mins
Source: Globenewswire
- Exclusive Licensing Agreement: Adlai Nortye has entered into an exclusive licensing agreement with ASK Pharm, granting ASK rights to develop and commercialize AN9025 in mainland China, Hong Kong, and Macao, with total consideration potentially reaching RMB 1.6 billion (approximately USD 230 million), significantly enhancing the company's market presence in China.
- Milestone Payments: The agreement includes over USD 20 million in near-term milestone payments, ensuring Adlai Nortye receives early-stage funding to accelerate the clinical development of AN9025, which is crucial for advancing its therapeutic pipeline.
- Market Potential: AN9025 is an oral small molecule pan-RAS (ON) inhibitor targeting RAS mutations across various tumor types, with plans to initiate Phase I clinical trials in Q1 2026, positioning it as a potential best-in-class treatment to meet the urgent demand for innovative cancer therapies in China.
- Strategic Collaboration: This partnership not only enhances Adlai Nortye's R&D capabilities but also leverages ASK Pharm's strong commercialization expertise in Greater China, thereby increasing the market potential for AN9025 and aiming to deliver high-value therapeutic solutions to patients.
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About ANL
Adlai Nortye Ltd. is a Cayman Islands-based investment holding company. The Company is involved in the research and development of pharmaceutical products. It is a clinical-stage company focused on the development of targeted and immune-modulating cancer therapies. It is advancing an oncology pipeline, with Buparlisib (AN2025), a pan-phosphoinositide 3-kinase (PI3K) inhibitor, being evaluated in a registrational Phase three trial (NCT04338399) for patients with recurrent or metastatic head and neck squamous cell cancer (HNSCC) that has progressed after prior anti-programmed death-ligand 1 (PD-L1) treatment. It is also advancing multiple drug candidates, including AN4005, an oral small molecule PD-L1 inhibitor; AN8025, a multifunctional fusion protein acting as a T cell and antigen-presenting cell (APC) modulator; and AN9025, an oral small molecule pan-rat sarcoma virus (RAS) inhibitor. The Company’s subsidiary, Alpine Bioscience Ltd. (Alpine BVI), is an investment holding company.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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