AbbVie and Genmab Release EPCORE DLBCL-1 Trial Results, Epcoritamab Significantly Improves Progression-Free Survival
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 17 2026
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Source: NASDAQ.COM
- Clinical Trial Results: The EPCORE DLBCL-1 trial demonstrated that Epcoritamab significantly improves progression-free survival (PFS) in patients with relapsed or refractory diffuse large B-cell lymphoma, indicating its potential clinical value in treatment.
- Patient Recruitment: The global study enrolled 483 patients, with 73% having received two or more prior therapies and being ineligible for high-dose chemotherapy and autologous stem cell transplant, highlighting the drug's importance in specific patient populations.
- Efficacy Assessment: While Epcoritamab showed additional benefits in complete response rates (CRR), duration of response (DoR), and time to next treatment, it did not demonstrate a statistically significant improvement in overall survival (OS), suggesting the need for further research into its long-term efficacy.
- Regulatory Progress: Epcoritamab has received regulatory approval in certain lymphoma indications in over 65 countries, with AbbVie and Genmab committed to advancing the drug's clinical programs to evaluate its potential across various hematologic malignancies.
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Analyst Views on ABBV
Wall Street analysts forecast ABBV stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ABBV is 253.26 USD with a low forecast of 218.00 USD and a high forecast of 289.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
22 Analyst Rating
15 Buy
7 Hold
0 Sell
Moderate Buy
Current: 220.430
Low
218.00
Averages
253.26
High
289.00
Current: 220.430
Low
218.00
Averages
253.26
High
289.00
About ABBV
AbbVie Inc. is a global, diversified research-based biopharmaceutical company. It is engaged in research and development, manufacturing, commercialization and sale of medicines and therapies. Its product portfolio includes Immunology, Oncology, Aesthetics, Neuroscience, Eye Care and Other Key Products. Immunology products include rheumatology, dermatology and gastroenterology. Oncology products include Imbruvica, Venclexta/Venclyxto, Elahere and Epkinly. Aesthetics portfolio consists of facial injectables, plastics and regenerative medicine, body contouring, and skincare products. Its Neuroscience products include Botox Therapeutic, Vraylar, Duopa and Duodopa, Ubrelvy, and Qulipta. Eye Care products include Ozurdex, Lumigan/Ganfort, Alphagan/Combigan, Restasis, and other eye care. Other key products include Mavyret/Maviret, Creon, and Linzess/Constella. Its investigational candidate, bretisilocin, is for the treatment of patients with moderate-to-severe major depressive disorder (MDD).
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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