IPO Performance: INSILICO (03696.HK), specializing in AI drug discovery, opened 4.56% higher and peaked at $68.7, marking a new listing high with a last price of $68.1, reflecting a 13.03% increase and a trading volume of 1.5069 million shares.

Milestone Payment Announcement: The company announced it received approximately $39 million from Menarini Group as a milestone payment following the completion of first-in-patient dosing in a Phase I clinical trial of MEN2501.

Stock Performance Overview: Various Hong Kong stocks showed mixed performance, with ZIJIN GOLD INTL and MINIMAX-WP experiencing significant gains, while others like GUMING and CHERY AUTO faced declines.

Short Selling Data: Short selling activity varied across stocks, with FWD showing a high short selling ratio of 16.999%, while NANSHAN AL INTL had a notably low ratio of 0.135%.

Market Capitalization Insights: The market capitalization at the end of the lock-up periods for these stocks ranges from 21.4 billion to 406.6 billion, indicating varying levels of investor interest and company valuations.

Future Lock-up Dates: Key lock-up expiration dates for these stocks are set between early 2026 and late 2026, which may impact trading strategies and stock performance as these dates approach.

Strategic Partnership: INSILICO and Qilu Pharmaceutical Group have formed a strategic partnership to collaborate on innovative drug development, focusing on cardiometabolic diseases.

Pharma.AI Utilization: INSILICO will use its Pharma.AI platform to design and optimize small molecule inhibitors, while Qilu Pharmaceutical will handle development and commercialization.

Contract Value: The agreement has a total contract value exceeding $931 million, which includes milestone payments and royalties based on net sales.

Market Impact: The collaboration aims to enhance the management of metabolic diseases through advanced drug development techniques.

Market Performance: The HSI closed up 44 points (0.17%) at 26,629, while the HSCEI fell 8 points (0.1%) to 9,114. The HSTECH rose 16 points (0.28%) to 5,762, with a total market turnover of HKD234.86 billion.

Chip Stocks Rally: Following a rally in memory chip stocks, ASMPT surged 6.3% to HKD108.2, while other chip makers like SMIC and HUA HONG SEMI also saw gains, reflecting positive sentiment in the sector.

Tech Stock Movements: BIDU-SW increased by 4.1% after JPMorgan raised its target price, while TENCENT and MEITUAN-W dipped slightly. BABA-W and JD-SW experienced modest gains.

Automotive and AI Stocks: BYD edged up 0.7%, while XPENG and SERES saw declines. AI stocks like UNISOUND and FOURTH PARADIGM dropped significantly, indicating volatility in the tech and automotive sectors.

Market Performance: The HSI fell 0.1% to 26,558, while the HSCEI and HSTECH also experienced declines of 0.3% and 0.4%, respectively, with a total half-day turnover of $131.628 billion.

Chip Stocks Surge: External memory chip stocks saw significant gains, with Disco hitting the day limit and ASMPT rising 6%, while other chip stocks like HUA HONG SEMI and INNOSCIENCE also posted positive performances.

Tech Stock Movements: KINGDEE INT'L surged 3.2% on profit expectations, while BIDU-SW rose 4.2% after positive forecasts from JPMorgan; however, major players like TENCENT and MEITUAN-W saw slight declines.

Economic Indicators: China's unemployment rate remained stable at 5.1%, and the Loan Prime Rate for January 2026 was unchanged at 3.00%, aligning with forecasts.