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Market Performance: U.S. stocks declined, with the Nasdaq Composite dropping over 350 points, while the Dow fell 0.60% and the S&P 500 decreased by 1.05%.

Sector Movements: Financial shares rose by 0.4%, but information technology stocks fell by 1.8%, reflecting mixed sector performance.

Notable Stock Movements: Uber's stock fell over 6% despite reporting strong revenue growth, while Evoke Pharma surged 133% after announcing an acquisition.

Global Market Trends: European and Asian markets mostly closed lower, with Japan's Nikkei 225 down 1.74% and the eurozone's STOXX 600 declining 0.30%.

Market Performance: U.S. stocks opened lower, with the Dow Jones dropping over 400 points, while the NASDAQ and S&P 500 also experienced declines of 1.59% and 1.17%, respectively.

Sector Movements: Consumer staples saw a slight increase of 0.5%, while information technology stocks fell by 1.8%.

Pfizer Earnings Report: Pfizer reported better-than-expected third-quarter earnings, with adjusted earnings of 87 cents, surpassing the consensus estimate, despite a 6% decline in sales year-over-year.

Equities Activity: Evoke Pharma's shares surged 135% following an acquisition announcement, while Prelude Therapeutics saw a 56% drop after signing an acquisition agreement that negatively impacted its stock.

Upwork's Strong Performance: Upwork Inc's shares surged 22.2% in pre-market trading after reporting third-quarter earnings of 36 cents per share, exceeding estimates, and raising its FY25 guidance.

Other Notable Gainers: Several stocks saw significant pre-market gains, including PTL Ltd (+67.4%), MSP Recovery Inc (+56.9%), and Denny’s Corp (+49.2%) following positive financial announcements.

Major Losers: Sarepta Therapeutics Inc experienced a sharp decline of 38.7% after disappointing third-quarter results, while Insperity Inc fell 31.3% due to worse-than-expected financial performance and lowered guidance.

Market Overview: The pre-market trading session showed a mix of gains and losses, with notable movements in various stocks, reflecting the impact of recent earnings reports and guidance updates.